摘 要：近年来超分子化学已经成为化学领域中的研究热点和最重要的发展方向之一，和传统化学中旧化学键的断裂与新化学键的生成不同，超分子化学更加注重通过弱键相互作用而实现的分子间的确定、识别与配位。在各种自组装涉及的弱键相互作用中，基于大环分子的主客体相互作用得到高度重视，其中大环分子环糊精及其衍生物因为独特的结构和性质已经发展成为一个重要的主体分子；作为客体分子的四苯乙烯（TPE）具有聚集诱导发光（AIE）效应，由于结构简单、化学稳定性好、容易修饰等特点，在很多方面得到了广泛的应用。本课题设计合成具有AIE效应的四苯乙烯衍生物作为客体分子，与具有疏水空腔的β-环糊精通过疏水相互作用自组装形成超分子组装体，利用TPE基团在β-环糊精空腔内与空腔外荧光强度的不同，来实现挥发性有机污染物的检测。该工作为超分子化学在荧光探针领域的应用提供了一种新的思路。
关键词：超分子； 主客体作用； 环糊精； TPE衍生物； 聚集诱导发光
Abstract：Supramolecular chemistry is a research hotspot and one of the most important development directions in the field of chemistry in recent years. It is different from the breakage of chemical bonds and the formation of new chemical bonds in traditional chemistry. Supramolecular chemistry is more concerned with determining, recognizing, and coordinating between molecules through weak bond interactions. Among the various weak bond interactions involved in self-assembly, the host-guest interactions based on macrocyclic molecules are highly valued. Because of their unique structure and properties, cyclodextrins and their derivatives have developed into an important host molecule. Tetrastyrene (TPE) has an aggregation-induced emission (AIE) effect, and has been widely used in the construction of solid fluorescent material systems due to its simple structure, good chemical stability, high electron transfer probability, and easy modification.In this thesis, the tetrastyryl derivatives with AIE effect were designed and synthesized. The derivatives self-assembled with β-cyclodextrin which has hydrophobic cavity through hydrophobic interaction to form supramolecular assemblies. The different fluorescence intensity of TPE groups in the β-cyclodextrin cavity and outside the cavity can be used to achieve the detection of volatile organic pollutants. This work provides a new idea for the application of supramolecular chemistry in the field of fluorescent probes.
Keywords: Supramolecular; host-guest interaction; cyclodextrin; TPE derivatives; Aggregation-induced emission
目 录
摘 要 II
Abstract III
目 录 IV
1.引言 1
1.1研究背景 1
1.1.1以环糊精为主体的主客体相互作用 1
1.1.2聚集诱导发光效应 3
1.1.3荧光材料在VOC检测方面的应用 6
1.2论文思路 8
2.分子设计与合成 9
2.1客体分子G的合成路线 9
3.实验部分 10
3.1原料及试剂 10
3.2测试仪器 10
3.3客体分子G的合成 11
4.表征结果与讨论 12
4.1客体分子G与β-环糊精之间主客体相互作用的表征 功能性荧光小分子的设计与合成:http://www.chuibin.com/huaxue/lunwen_205682.html